Autoimmune, Circadian Clock, and Metabolism. Or...Why I Sleep At Night

A chai latte and a good friend have to be the best combination this side of heaven! This is why I love when we get a chance to meet up and catch up. :)

A couple of chats ago we discussed our body's circadian clocks and why it is important to get that thing regulated. But because our time was short I forgot to mention a few things.

I know, right!? God's design of the body does provide an endless supply of conversation topics! It is just so fascinating, even if it took us becoming autoimmuners to think so. :)

I mentioned at our last talk that nothing is in a vacuum and how everything is interrelated, do you remember? 

Well, you will see how that stays true when it comes to our circadian clocks. 

Just to refresh your memory, our circadian clock controls a variety of functions including body temperature, behavioral and physiological functions, hormone secretion, bowel elimination and immune function just to name a few...

Circadian mismatches have a significant negative effect on cells, tissues, and well, basically a bunch of stuff. A mismatch can manifest as chronic health conditions like digestive disorders, depression, dementia, cancer, diabetes, and, our friend, autoimmune.

Ok, let's dive into this exquisite topic! 

We'll wade into the shallow end with the circadian clocks effect on our sleep patterns before we belly flop into the deep end with how it also affects our muscles and metabolism...

Who knew the circadian clock had ANY effect on our muscles? Which is just more evidence that EVERYTHING is interrelated! 

We all know that our body regenerates while we are snoozing away, but what does that look like? Well, it helps stabilize our immune systems, repairs cells, and is when new information is processed into long-term memories. (So careful what you feed your soul...)

We've talked about melatonin in the past, so I'll just mention, for the sake of this conversation, that it plays a significant role in the regulation of our circadian clocks. If we are not lowering the lights or getting to bed at a reasonable hour this can hinder melatonin being distributed at the proper time; if we are not getting enough natural light, it can cause a hiccup in its production.


I was at Camp Shoshanah, a bible study/discipleship camp, this summer, and one of my bunk mates mentioned to me that I fall asleep within seconds of saying "Goodnight". 


Now, this has not historically been the case. I used to toss and turn taking an hour or two to finally get to sleep, waking up when I heard a nat blink. But since setting my circadian clock, I now fall asleep quickly and stay asleep all night. 


Not you? Not to worry, we can fix that! 

Ok, time for our belly flop…

One of the more fascinating studies I've combed through is learning how our muscles ask for the energy they need from our fat storage tissues!

Who knew!? 

Makes you wonder if they say please and thank you. And I'm thinking my tissues don't like to share much...

Just kidding...

But seriously, it is truly fascinating to understand this connection. What is even more fascinating is how this connection is dependent on our circadian clocks! 

You see, we have one gene involved in the muscle and another gene involved in the fat tissue to make this signaling pathway work. This pathway is coordinated with the body's circadian clock which regulates the storage and the release of fat.

Exquisitely designed!

We also have a certain gene that is crucial for controlling how many fatty acids you have in circulation at a given time, and help regulate insulin level, which tells the body whether to store energy as fat or to release it.

What are fatty acids, you ask?

They are important dietary sources of fuel because when metabolized they yield large quantities of energy (ATP). 

Now, this speaks to the importance of when you eat because this signaling between the muscles and our fat storage is based on the energy needs of the muscles and is regulated by our...

You guessed it!

...circadian clock.

This realization ties nicely into how our circadian clock functions in managing the balance of energy. Because, you see, our gut microbiome and our metabolism are like two peas in a pod! 

Ha! That made your head tilt in wonder! :D

But it is true! You see, our gut should contain over 30,000 species of bacteria, viruses, fungi, and other similar stuff. With those species providing over a trillion copies of themselves to establish a well-stocked bunker. 

These organisms are essential for our well-being as they affect a variety of functions like early immune and metabolic development, deterrence of pathogens, regulation of gene expression, and the function of many organ systems.

Loss or dysfunction of the microbiome can have severe, life threatening consequences. This is not hyperbole; this is one of the main reasons we developed an autoimmune. 

When we have a disturbance in our body and/or the microbiome, our metabolic balance can become disrupted, which can lead to obesity and other crappy diseases.

It appears that our microbiome and metabolism are inextricably linked by our circadian clock. This isn't a one-way street, this is bidirectional, and therefore it's essential for these systems to be synchronized. 

To say that a different way...

Our circadian clock needs data from our microbiome and our metabolism to function properly; our microbiome and metabolism need data from our circadian clock to function properly. 

So changes in our circadian clocks are accompanied by changes in our metabolism, behavior, and other typical functions our bodies perform. 

What does this mean for us autoimmuners?

When we don't abide by the natural cycles we were designed to work with, it amounts to waaaaayyyyy more than a bad nights sleep. This affects our mental health, our emotional health, and our physical health.

Over time this will cause more and more health problems. As we continue to live in an artificially lit world, inhibit our exposure to the sun, drink and eat poison, and ignore the day and night cycles, can we be surprised that we are getting sicker with every generation


Children have adult diseases now, autoimmunes are skyrocketing, as are other Neolithic diseases! And most people are looking to the very industries that caused this problem for the solution. #smh

We autoimmuners know, that is not where the answers lie. 

How do we know this? Because most of us have tried it the conventional way, just to be given up on.

Where do the answers lie, you ask?

Before the 20th century, the leading cause of death was infectious diseases.  Today they are Neolithic. Meaning they are due to trying to live in contrary to how God designed us to live. (I just made that up, you won't get that definition if you Bing it.) 

Think about that for a sec. 

It was after WWII that we started spraying and genetically modifying our food, hiding from the sun, were told dirt is dirty, and we must avoid bacteria. Then because of electricity, we stay up to all hours; able, for the first time in history, to ignore nature's cycles. 

We have naively declared that we can set our own time clock. 

Well... we can't. The explosion of diseases is proving that. 

Get back to what God provided and designed us to utilize for our health. 

We have crated a training video that will help you to understand how to reverse your autoimmune disorder.

You can watch the '5 Steps To Reversing Autoimmune Disorders' here

It truly is that simple!

Join other autoimmuners on the Facebook page Autoimmune Survival, to get little autoimmune management nuggets.

Trust me when I say, I know these changes are going to seem a little strange at first. But it’s important to understand that implementing small changes, like this, into your life can bring significant improvements in your health, as every little step brings you that much closer to your health goals. I suffered from an autoimmune for years, but by implementing habits like this into my life, I am able to participate in life again.

The information in this blog is for educational purposes only and is not intended as medical advice in any way, nor claims cure or treatment of any medical condition. In no event shall Kelly Sato be liable for any consequential damages arising out of any use of, or reliance on any content or materials contained herein, neither shall Kelly Sato be liable for any content of any external internet sites or services listed. Always consult your own licensed MD if you are in any way concerned about your health.